Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19.
Identifieur interne : 000928 ( Main/Exploration ); précédent : 000927; suivant : 000929Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19.
Auteurs : Eve Garrigues [France] ; Paul Janvier [France] ; Yousra Kherabi [France] ; Audrey Le Bot [France] ; Antoine Hamon [France] ; Hélène Gouze [France] ; Lucile Doucet [France] ; Sabryne Berkani [France] ; Emma Oliosi [France] ; Elise Mallart [France] ; Félix Corre [France] ; Virginie Zarrouk [France] ; Jean-Denis Moyer [France] ; Adrien Galy [France] ; Vasco Honsel [France] ; Bruno Fantin [France] ; Yann Nguyen [France]Source :
- The Journal of infection [ 1532-2742 ] ; 2020.
Abstract
OBJECTIVE
To assess post-discharge persistent symptoms and health-related quality of life (HRQoL) of patients hospitalized in a COVID-19 ward unit more than 100 days after their admission.
METHODS
All eligible patients were contacted by phone by trained physicians and were asked to answer to a dedicated questionnaire. Patients managed in hospital ward without needing intensive care were compared with those who were transferred in intensive care units (ICU).
RESULTS
We included 120 patients after a mean (±SD) of 110.9 (±11.1) days following admission. The most frequently reported persistent symptoms were fatigue (55%), dyspnoea (42%), loss of memory (34%), concentration and sleep disorders (28% and 30.8%, respectively). Comparisons between ward- and ICU patients led to no statistically significant differences regarding those symptoms. In both group, EQ-5D (mobility, self-care, pain, anxiety or depression, usual activity) was altered with a slight difference in pain in the ICU group.
CONCLUSION
Most patients requiring hospitalization for COVID-19 still have persistent symptoms. While there were few differences between HRQoL between ward and ICU patients, our findings must be confirmed in larger cohorts, including more severe patients.
DOI: 10.1016/j.jinf.2020.08.029
PubMed: 32853602
PubMed Central: PMC7445491
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19.</title><author><name sortKey="Garrigues, Eve" sort="Garrigues, Eve" uniqKey="Garrigues E" first="Eve" last="Garrigues">Eve Garrigues</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Janvier, Paul" sort="Janvier, Paul" uniqKey="Janvier P" first="Paul" last="Janvier">Paul Janvier</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiology, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiology, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Kherabi, Yousra" sort="Kherabi, Yousra" uniqKey="Kherabi Y" first="Yousra" last="Kherabi">Yousra Kherabi</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Le Bot, Audrey" sort="Le Bot, Audrey" uniqKey="Le Bot A" first="Audrey" last="Le Bot">Audrey Le Bot</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Hamon, Antoine" sort="Hamon, Antoine" uniqKey="Hamon A" first="Antoine" last="Hamon">Antoine Hamon</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Gouze, Helene" sort="Gouze, Helene" uniqKey="Gouze H" first="Hélène" last="Gouze">Hélène Gouze</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Doucet, Lucile" sort="Doucet, Lucile" uniqKey="Doucet L" first="Lucile" last="Doucet">Lucile Doucet</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Berkani, Sabryne" sort="Berkani, Sabryne" uniqKey="Berkani S" first="Sabryne" last="Berkani">Sabryne Berkani</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Oliosi, Emma" sort="Oliosi, Emma" uniqKey="Oliosi E" first="Emma" last="Oliosi">Emma Oliosi</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Mallart, Elise" sort="Mallart, Elise" uniqKey="Mallart E" first="Elise" last="Mallart">Elise Mallart</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Corre, Felix" sort="Corre, Felix" uniqKey="Corre F" first="Félix" last="Corre">Félix Corre</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Zarrouk, Virginie" sort="Zarrouk, Virginie" uniqKey="Zarrouk V" first="Virginie" last="Zarrouk">Virginie Zarrouk</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Moyer, Jean Denis" sort="Moyer, Jean Denis" uniqKey="Moyer J" first="Jean-Denis" last="Moyer">Jean-Denis Moyer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Anaesthesiology and Intensive Care, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Anaesthesiology and Intensive Care, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Galy, Adrien" sort="Galy, Adrien" uniqKey="Galy A" first="Adrien" last="Galy">Adrien Galy</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Honsel, Vasco" sort="Honsel, Vasco" uniqKey="Honsel V" first="Vasco" last="Honsel">Vasco Honsel</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Fantin, Bruno" sort="Fantin, Bruno" uniqKey="Fantin B" first="Bruno" last="Fantin">Bruno Fantin</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Nguyen, Yann" sort="Nguyen, Yann" uniqKey="Nguyen Y" first="Yann" last="Nguyen">Yann Nguyen</name><affiliation wicri:level="3"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France; Centre for Epidemiology and Population Health, INSERM U1018, Villejuif, France. Electronic address: yann.nguyen2@aphp.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France; Centre for Epidemiology and Population Health, INSERM U1018, Villejuif</wicri:regionArea><placeName><settlement type="city">Villejuif</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32853602</idno><idno type="pmid">32853602</idno><idno type="doi">10.1016/j.jinf.2020.08.029</idno><idno type="pmc">PMC7445491</idno><idno type="wicri:Area/Main/Corpus">000336</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000336</idno><idno type="wicri:Area/Main/Curation">000336</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000336</idno><idno type="wicri:Area/Main/Exploration">000336</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19.</title><author><name sortKey="Garrigues, Eve" sort="Garrigues, Eve" uniqKey="Garrigues E" first="Eve" last="Garrigues">Eve Garrigues</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Janvier, Paul" sort="Janvier, Paul" uniqKey="Janvier P" first="Paul" last="Janvier">Paul Janvier</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiology, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiology, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Kherabi, Yousra" sort="Kherabi, Yousra" uniqKey="Kherabi Y" first="Yousra" last="Kherabi">Yousra Kherabi</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Le Bot, Audrey" sort="Le Bot, Audrey" uniqKey="Le Bot A" first="Audrey" last="Le Bot">Audrey Le Bot</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Hamon, Antoine" sort="Hamon, Antoine" uniqKey="Hamon A" first="Antoine" last="Hamon">Antoine Hamon</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Gouze, Helene" sort="Gouze, Helene" uniqKey="Gouze H" first="Hélène" last="Gouze">Hélène Gouze</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Doucet, Lucile" sort="Doucet, Lucile" uniqKey="Doucet L" first="Lucile" last="Doucet">Lucile Doucet</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Berkani, Sabryne" sort="Berkani, Sabryne" uniqKey="Berkani S" first="Sabryne" last="Berkani">Sabryne Berkani</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Oliosi, Emma" sort="Oliosi, Emma" uniqKey="Oliosi E" first="Emma" last="Oliosi">Emma Oliosi</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Mallart, Elise" sort="Mallart, Elise" uniqKey="Mallart E" first="Elise" last="Mallart">Elise Mallart</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Corre, Felix" sort="Corre, Felix" uniqKey="Corre F" first="Félix" last="Corre">Félix Corre</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Zarrouk, Virginie" sort="Zarrouk, Virginie" uniqKey="Zarrouk V" first="Virginie" last="Zarrouk">Virginie Zarrouk</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Moyer, Jean Denis" sort="Moyer, Jean Denis" uniqKey="Moyer J" first="Jean-Denis" last="Moyer">Jean-Denis Moyer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Anaesthesiology and Intensive Care, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Anaesthesiology and Intensive Care, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Galy, Adrien" sort="Galy, Adrien" uniqKey="Galy A" first="Adrien" last="Galy">Adrien Galy</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Honsel, Vasco" sort="Honsel, Vasco" uniqKey="Honsel V" first="Vasco" last="Honsel">Vasco Honsel</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Fantin, Bruno" sort="Fantin, Bruno" uniqKey="Fantin B" first="Bruno" last="Fantin">Bruno Fantin</name><affiliation wicri:level="1"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy</wicri:regionArea><wicri:noRegion>Clichy</wicri:noRegion><wicri:noRegion>Clichy</wicri:noRegion></affiliation></author><author><name sortKey="Nguyen, Yann" sort="Nguyen, Yann" uniqKey="Nguyen Y" first="Yann" last="Nguyen">Yann Nguyen</name><affiliation wicri:level="3"><nlm:affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France; Centre for Epidemiology and Population Health, INSERM U1018, Villejuif, France. Electronic address: yann.nguyen2@aphp.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France; Centre for Epidemiology and Population Health, INSERM U1018, Villejuif</wicri:regionArea><placeName><settlement type="city">Villejuif</settlement></placeName></affiliation></author></analytic><series><title level="j">The Journal of infection</title><idno type="eISSN">1532-2742</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>To assess post-discharge persistent symptoms and health-related quality of life (HRQoL) of patients hospitalized in a COVID-19 ward unit more than 100 days after their admission.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>All eligible patients were contacted by phone by trained physicians and were asked to answer to a dedicated questionnaire. Patients managed in hospital ward without needing intensive care were compared with those who were transferred in intensive care units (ICU).</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>We included 120 patients after a mean (±SD) of 110.9 (±11.1) days following admission. The most frequently reported persistent symptoms were fatigue (55%), dyspnoea (42%), loss of memory (34%), concentration and sleep disorders (28% and 30.8%, respectively). Comparisons between ward- and ICU patients led to no statistically significant differences regarding those symptoms. In both group, EQ-5D (mobility, self-care, pain, anxiety or depression, usual activity) was altered with a slight difference in pain in the ICU group.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Most patients requiring hospitalization for COVID-19 still have persistent symptoms. While there were few differences between HRQoL between ward and ICU patients, our findings must be confirmed in larger cohorts, including more severe patients.</p></div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32853602</PMID><DateRevised><Year>2020</Year><Month>09</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1532-2742</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Aug</Month><Day>25</Day></PubDate></JournalIssue><Title>The Journal of infection</Title><ISOAbbreviation>J. Infect.</ISOAbbreviation></Journal><ArticleTitle>Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">S0163-4453(20)30562-4</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jinf.2020.08.029</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To assess post-discharge persistent symptoms and health-related quality of life (HRQoL) of patients hospitalized in a COVID-19 ward unit more than 100 days after their admission.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">All eligible patients were contacted by phone by trained physicians and were asked to answer to a dedicated questionnaire. Patients managed in hospital ward without needing intensive care were compared with those who were transferred in intensive care units (ICU).</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">We included 120 patients after a mean (±SD) of 110.9 (±11.1) days following admission. The most frequently reported persistent symptoms were fatigue (55%), dyspnoea (42%), loss of memory (34%), concentration and sleep disorders (28% and 30.8%, respectively). Comparisons between ward- and ICU patients led to no statistically significant differences regarding those symptoms. In both group, EQ-5D (mobility, self-care, pain, anxiety or depression, usual activity) was altered with a slight difference in pain in the ICU group.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Most patients requiring hospitalization for COVID-19 still have persistent symptoms. While there were few differences between HRQoL between ward and ICU patients, our findings must be confirmed in larger cohorts, including more severe patients.</AbstractText><CopyrightInformation>Copyright © 2020. Published by Elsevier Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Garrigues</LastName><ForeName>Eve</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Janvier</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Radiology, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kherabi</LastName><ForeName>Yousra</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Le Bot</LastName><ForeName>Audrey</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hamon</LastName><ForeName>Antoine</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gouze</LastName><ForeName>Hélène</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Doucet</LastName><ForeName>Lucile</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Berkani</LastName><ForeName>Sabryne</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oliosi</LastName><ForeName>Emma</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mallart</LastName><ForeName>Elise</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Corre</LastName><ForeName>Félix</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zarrouk</LastName><ForeName>Virginie</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moyer</LastName><ForeName>Jean-Denis</ForeName><Initials>JD</Initials><AffiliationInfo><Affiliation>Department of Anaesthesiology and Intensive Care, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Galy</LastName><ForeName>Adrien</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Honsel</LastName><ForeName>Vasco</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fantin</LastName><ForeName>Bruno</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nguyen</LastName><ForeName>Yann</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Departement of Internal Medicine, AP-HP.Nord, Beaujon Hospital, University of Paris, Clichy, France; Centre for Epidemiology and Population Health, INSERM U1018, Villejuif, France. Electronic address: yann.nguyen2@aphp.fr.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016422">Letter</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>08</Month><Day>25</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Infect</MedlineTA><NlmUniqueID>7908424</NlmUniqueID><ISSNLinking>0163-4453</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Covid-19</Keyword><Keyword MajorTopicYN="N">Health-related quality of life</Keyword><Keyword MajorTopicYN="N">Persistent symptoms</Keyword></KeywordList><CoiStatement>Declaration of Competing Interest None of the authors declared any competing interest in link with the present study.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>08</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>08</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>8</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>8</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>8</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32853602</ArticleId><ArticleId IdType="pii">S0163-4453(20)30562-4</ArticleId><ArticleId IdType="doi">10.1016/j.jinf.2020.08.029</ArticleId><ArticleId IdType="pmc">PMC7445491</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>France</li></country><settlement><li>Villejuif</li></settlement></list><tree><country name="France"><noRegion><name sortKey="Garrigues, Eve" sort="Garrigues, Eve" uniqKey="Garrigues E" first="Eve" last="Garrigues">Eve Garrigues</name></noRegion><name sortKey="Berkani, Sabryne" sort="Berkani, Sabryne" uniqKey="Berkani S" first="Sabryne" last="Berkani">Sabryne Berkani</name><name sortKey="Corre, Felix" sort="Corre, Felix" uniqKey="Corre F" first="Félix" last="Corre">Félix Corre</name><name sortKey="Doucet, Lucile" sort="Doucet, Lucile" uniqKey="Doucet L" first="Lucile" last="Doucet">Lucile Doucet</name><name sortKey="Fantin, Bruno" sort="Fantin, Bruno" uniqKey="Fantin B" first="Bruno" last="Fantin">Bruno Fantin</name><name sortKey="Galy, Adrien" sort="Galy, Adrien" uniqKey="Galy A" first="Adrien" last="Galy">Adrien Galy</name><name sortKey="Gouze, Helene" sort="Gouze, Helene" uniqKey="Gouze H" first="Hélène" last="Gouze">Hélène Gouze</name><name sortKey="Hamon, Antoine" sort="Hamon, Antoine" uniqKey="Hamon A" first="Antoine" last="Hamon">Antoine Hamon</name><name sortKey="Honsel, Vasco" sort="Honsel, Vasco" uniqKey="Honsel V" first="Vasco" last="Honsel">Vasco Honsel</name><name sortKey="Janvier, Paul" sort="Janvier, Paul" uniqKey="Janvier P" first="Paul" last="Janvier">Paul Janvier</name><name sortKey="Kherabi, Yousra" sort="Kherabi, Yousra" uniqKey="Kherabi Y" first="Yousra" last="Kherabi">Yousra Kherabi</name><name sortKey="Le Bot, Audrey" sort="Le Bot, Audrey" uniqKey="Le Bot A" first="Audrey" last="Le Bot">Audrey Le Bot</name><name sortKey="Mallart, Elise" sort="Mallart, Elise" uniqKey="Mallart E" first="Elise" last="Mallart">Elise Mallart</name><name sortKey="Moyer, Jean Denis" sort="Moyer, Jean Denis" uniqKey="Moyer J" first="Jean-Denis" last="Moyer">Jean-Denis Moyer</name><name sortKey="Nguyen, Yann" sort="Nguyen, Yann" uniqKey="Nguyen Y" first="Yann" last="Nguyen">Yann Nguyen</name><name sortKey="Oliosi, Emma" sort="Oliosi, Emma" uniqKey="Oliosi E" first="Emma" last="Oliosi">Emma Oliosi</name><name sortKey="Zarrouk, Virginie" sort="Zarrouk, Virginie" uniqKey="Zarrouk V" first="Virginie" last="Zarrouk">Virginie Zarrouk</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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